Siglec 10 antibody
WebAnti-SIGLEC10 antibody produced in rabbit affinity isolated antibody; Synonyms: Anti-MGC126774,Anti-PRO940,Anti-SIGLEC-10,Anti-SLG2; find Sigma-Aldrich-SAB2103423 … WebIn cancer it is important to consider the mode of action of CD24-Fc. The binding to Siglec-10 on immune effector cells as an agonist could render cells more immunosuppressive. In …
Siglec 10 antibody
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WebAbcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that … WebNov 10, 2024 · AK007 is a humanized Siglec-10 antagonist antibody designed to block Siglec-10 interaction with all known ligands (CD24, CD52, and VAP-1). By targeting Siglec …
WebRabbit Polyclonal Anti-SIGLEC10 Antibody against Human sialic acid binding Ig-like lectin 10. Antibody validation: Validated for Immunohistochemistry and Western Blot. Support; … WebSiglec-G is the apparent ortholog of human Siglec-10 (4). The human Siglec-10 cDNA encodes a 697 amino acid (aa) precursor that includes a 16 aa signal sequence, a 534 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 126 aa cytoplasmic domain. The ECD contains one Ig-like V‑type domain and four Ig-like C2-type domains ...
WebSiglec-G is the apparent ortholog of human Siglec-10 (4). The human Siglec-10 cDNA encodes a 697 amino acid (aa) precursor that includes a 16 aa signal sequence, a 534 aa … WebSIGLEC10 antibody LS-C187565 is an unconjugated mouse monoclonal antibody to human SIGLEC10. Validated for Flow. Products. Research Areas. COVID-19. Resources. ... (NK) cells. Structurally, Siglec-10 is most similar to the CD33-related group of Siglecs, and preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic ...
WebProduct Specific Information. Mouse anti Human Siglec-10 antibody, clone 5G6 recognizes human Siglec-10 (Sialic acid-binding Ig-like lectin 10), a putative adhesion molecule and …
Like most but not all other Siglecs, Siglec-10 bears an ITIM (Immunoreceptor tyrosine-based inhibitory motif) within its cytoplasmic domain. Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to … See more Sialic acid-binding Ig-like lectin 10 is a protein that in humans is encoded by the SIGLEC10 gene. Siglec-G is often referred to as the murine paralog of human Siglec-10 See more SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor … See more • Li N, Zhang W, Wan T, et al. (2001). "Cloning and characterization of Siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells". J. Biol. Chem. 276 (30): 28106–12. doi:10.1074/jbc.M100467200. PMID 11358961. See more suckered limb crossword clueWebJul 4, 2014 · Siglec-10 (human homolog of mouse Siglec-G) was detected on all B cells and also subsets of human leukocytes including eosinophils, monocytes and a minor … suckered limb crosswordWebSiglec-10 Fc (Mouse IgFc) at 10 μg ml was incubated with anti-Siglec-10 antibodies and the Siglec-10Fc/antibody complexes were incubated with tumor cell lines and then washed. Selected antibodies blocked the binding of Siglec-10 … paintings n stuffWebJul 31, 2024 · The blockade of Siglec-10 using monoclonal antibodies augmented the phagocytic ability of macrophages, thereby confirming a role for Siglec-10 in inhibiting … paintingsns.comWebThe cell-expression patterns are indicated on the basis of antibody labelling, except for Siglec-14 and Siglec-15, which have not yet been determined. The brackets indicate low … painting snowy mountains in acrylicWebSIGLEC 10 antibody. Siglec G antibody. Siglec-like protein 2 antibody. SIGLEC10 antibody. Siglecg antibody. SLG2 antibody : Protein information supplied by UniProt . Accessories. … suckered limbpainting snow with oil paint