WebThe blood transcriptome was examined in relation to disease severity in type I myotonic dystrophy (DM1) patients who participated in the Observational Prolonged Trial In DM1 to Improve QoL- Standards (OPTIMISTIC) study. This sought to (a) ascertain if transcriptome changes were associated with increasing disease severity, as measured by the muscle … WebHere, we’ve pulled together the most up to date information for a range of information-seekers – from the person newly diagnosed to the physical therapist seeking exercise …

Myotonic Dystrophy: Start Your Journey Here

WebSep 26, 2024 · INTRODUCTION. Myotonic dystrophy type 1 (DM1) and myotonic dystrophy type 2 (DM2) are autosomal dominant, multisystem disorders characterized by skeletal … WebMyotonic Dystrophy Start-up Resource Listing: All Core and Supplemental–Highly Recommended CDEs recommended for Myotonic Dystrophy study start-up. ... A publication related to the Myotonic Dystrophy CDE initiative will be written at a later date. The citation for this publication will be included on this site as soon as it is available. the yellow ghost

Myotonic Dystrophy Support & Care

http://www.myotonicdystrophysupportgroup.org/myotonic-dystrophy-and-the-eye/ WebSep 30, 2013 · Important data come from the field of hereditary muscle dystrophies, like Duchenne muscle dystrophy and Myotonic dystrophies, rare diseases affecting 1 in 7000–15,000 newborns and is characterized by severe to mild muscle weakness associated with cardiac involvement. ... An up-to-date list of the identified targets of miR-1, miR-133 … WebFeb 25, 2003 · Results: Among affected individuals 90% had electrical myotonia, 82% weakness, 61% cataracts, 23% diabetes, and 19% cardiac involvement. Because of the repeat tract’s unprecedented size (mean ∼5,000 CCTGs) and somatic instability, expansions were detectable by Southern analysis in only 80% of known carriers. safety watch australia portal