High affinity copper uptake protein 1

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August undefined, 2024

Web1 de abr. de 2002 · Copper uptake High-affinity copper transport proteins Physiological and biochemical studies many years ago suggested the presence of at least two independent activities responsible for copper uptake in eukaryotic cells, of distinct affinities and capacities for copper [6]. WebCopper (Cu) is an essential trace element for growth and development and abnormal Cu levels are associated with anemia, metabolic disease and cancer. Evolutionarily …

X-ray structures of the high-affinity copper transporter Ctr1

WebBoth these receptors are transmembrane glycoproteins. TfR1 is a high affinity ubiquitously expressed receptor while expression of TfR2 is restricted to certain cell types and is unaffected by intracellular iron … WebProtein target information for High affinity copper uptake protein 1 (Norway rat). Find diseases associated with this biological target and compounds tested against it in … northern africa countries map

O15431 - UniProt

Web21 de mar. de 2024 · SLC31A1 (Solute Carrier Family 31 Member 1) is a Protein Coding gene. Diseases associated with SLC31A1 include Wilson Disease and Combat Disorder . Among its related pathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Copper homeostasis . Web8 de jul. de 1997 · We propose this gene as a candidate for high-affinity copper uptake in humans and by analogy have named it h CTR1. The hCTR1 and yeast CTR1 predicted transmembrane proteins are 29% identical, but the human protein is substantially smaller in both the extracellular metal-binding and intracellular domains. WebThe major human high-affinity copper uptake protein, human copper transporter hCTR1, was recently shown to be at the basolateral or blood side of both intestinal and renal ... northern afghanistan/mazar-i-sharif

LOC106152599 high affinity copper uptake protein 1 []

High affinity copper uptake protein 1 (Norway rat) - PubChem

WebThese high-affinity copper transporters exist in all eukaryotes and their discovery has provided new insights into how cells acquire and regulate this essential nutrient. The … WebHMDBP08240. Secondary Accession Numbers. 13952. Name. High affinity copper uptake protein 1. Synonyms. Copper transporter 1. Solute carrier family 31 member 1. hCTR1. how to revive teammates in gpo battle royaleWebCrystal structure of the high-affinity copper transporter Ctr1 PDB DOI: 10.2210/pdb6M97/pdb Classification: TRANSPORT PROTEIN Organism (s): Salmo salar, Escherichia coli Expression System: Komagataella phaffii GS115 Mutation (s): Yes Membrane Protein: Yes OPM PDBTM MemProtMD mpstruc Deposited: 2024-08-22 … northern africa countries list

"WebHigh affinity copper uptake protein 1 DrugBank Online with DrugBank on your side. High affinity copper uptake protein 1 Details Name High affinity copper uptake … " - High affinity copper uptake protein 1

High affinity copper uptake protein 1

Is copper a new target to counteract the progression of chronic ...

Web15 de abr. de 2024 · High affinity copper uptake protein 1 (pig) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers... Web27 de mar. de 2024 · The high-affinity Cu transporter Ctr1 ( Km ≈ 2 μM) 4, an integral membrane protein localized to the plasma membrane and endosomal vesicles, mediates cellular Cu uptake in eukaryotes from...

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WebCTR1 undergoes MAC1-dependent degradation at the membrane in cells exposed to high copper levels and in a fashion independent of endocytosis. Present with 1180 molecules/cell in log phase SD medium. Catalytic activity Cu2+(in) = Cu2+(out) 2 publications This reaction proceeds in the backward direction. Source: Rhea 28703 Hide … Web149 Likes, 9 Comments - Joshua Rubin (@realfoodgangstas) on Instagram: "10 Things You Can Do Today to Replenish Zinc Status to Support Thyroid Health Lets talk about ...

Web16 de mar. de 2010 · Copper and iron are essential elements employed in pathways that are conserved in all kingdoms of life. In eukaryotes, several interdependent connections between copper and iron homeostasis have been described previously ().For example, high-affinity iron uptake in Saccharomyces cerevisiae is mediated by multicopper … Web12 de abr. de 2024 · To overcome this challenge, bacteria synthesize high-affinity iron-binding molecules called siderophores, which are recognized by specific transporters on the cell surface. Trojan horse antibiotics have evolved to hijack these transporters for uptake across the outer membrane (OM).

WebGene ID: 105284566, updated on 12-Aug-2024. Summary Other designations. high affinity copper uptake protein 1 WebProtein High affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence …

WebLOC108023471 high affinity copper uptake protein 1 [] Gene ID: 108023471, updated on 15-Oct-2024. Summary Other designations. high affinity ...

High affinity copper uptake protein 1 (CTR1) is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, … Ver mais In 2024, a new autosomal-recessive disease was discovered that is caused by mutations of the CTR1 gene. The disease is characterized by profound deficiency of copper in the central nervous system and presents with … Ver mais • Solute carrier family Ver mais • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". … Ver mais how to revive teammates in dark and darkerWebMonoclonal Antibody to Copper Transporter 1 (COPT1) SLC31A1; CTR1; hCTR1; High Affinity Copper Uptake Protein 1; Solute Carrier Family 31 Member 1 Item Properties: Gene >> Copper Transporter 1 Product No.: MAE493Hu21 >> Metabolic pathway Product No.MAE493Hu21 Organism SpeciesHomo sapiens (Human) Same name, Different … how to revive tulipsWebAntigen: High affinity copper uptake protein 1 Available to For-Profits: Yes Antigen Species: Human Hybridoma Cells Available (Non-Profit): No Isotype: MIgG2b Depositor: Clinical Proteomics Technologies for Cancer Host Species: mouse Antigen Sequence: Positive Tested Species Reactivity: Human Depositors Institution: National Cancer Institute how to revive the ender dragonWeb1 de abr. de 2024 · The CTR1 gene of Saccharomyces cerevisiae encodes a protein required for high affinity copper uptake. The protein is expressed on the plasma membrane, is heavily glycosylated with O-linkages, and ... how to revive vinyl sidingWeb15 de mar. de 1996 · Two proteins in the plasma membrane of yeast—a multicopper oxidase, encoded by the FET3 gene, and a permease, encoded by the FTR1 gene—were shown to mediate high-affinity iron uptake. FET3 expression was required for FTR1 protein to be transported to the plasma membrane. how to revive tulips droopingWebProtein target information for High affinity copper uptake protein 1 (Sumatran orangutan). Find diseases associated with this biological target and compounds tested against it in … how to revive technobladeWeb19 de out. de 2024 · HD is a neurodegenerative disorder, caused by a dominant polyglutamine expansion within the N-terminus of the huntingtin protein and is characterized by oxidative stress and striatal degeneration. 63 In the striatum of HD brains, high Cu and iron concentrations have been detected. 64 Studies by Fox and colleagues (2007) have … how to revive the npc in sons of the forest